Advanced Methods for Diagnostic Imaging 2014

The course is organized as a consecutive course to VAMDI 2013 at the Faculty of Biomedical Engineering in Kladno.

The course consists of two parts:

Part I (January 14 and 15, 2014): Lectures of Professor Christoph Rose-Petruck, Brown University, Dept. of Chemistry, Providence, RI, USA and seminars about research results of CTU students.

Part II (January 20 and 21, 2014) Lectures: Professor Norbert Lange, School of Pharmaceutical Sciences, University of Geneva, Switzerland and seminars about research results of CTU students.

Synopsis

Part I:

Lecture 1: Advanced X-ray imaging methods and performance comparison to MRI (Ch. Rose-Petruck)

The lectures will explore the interface between x-ray imaging and magnetic resonance imaging (MRI). The most sensitive x-ray imaging modalities will be reviewed.

Lecture 2: MRI imaging concept and applications (Ch. Rose-Petruck)

An introduction into MRI will be presented. The sensitivities of MRI and x-ray imaging for the detection of immunolabeled cancers will be discussed.

Seminar 1: Capillary Discharge Plasma as a Source of Soft X-ray Radiation (J. Hubner)

A theoretical study of capillary discharge plasma as a source of coherent radiation on Balmer α transition from level n = 3 to n = 2 of hydrogen-like ions (boron, carbon, and nitrogen) is presented.

Seminar 2: Capillary Discharge Driver for 13.4 nm Laser (M. Nevrkla)

Progress in development of driver capable to deliver >70 kA with rise-time ~30 ns into 22 cm long capillary is presented.

Seminar 3: Optical guiding of ultra short laser pulses in capillary discharge (M. Tamáš)

Capillary discharge as pre-formed plasma column for optical guiding of femtosecond laser pulses is presented. Dynamics of the discharge is discussed, MHD simulations are compared with experimental results.

Part II:

Lecture 1: Optical Theranostics: Theranostics. PDT Agents. 5-ALA and its derivatives: Basics and recent results  (N. Lange)

Lecture 2: Biophotonics on a Molecular Level: Microscopy. Fluorescence Microscopy. Confocal Microscopy. Two Photon Microscopy. Fluorescent Proteins. Superresolution Microscopy. (N. Lange)

Seminar 1: Luminescent nanoparticles for X-ray initiated photodynamic therapy (P. Brůža)

The properties and future applications of scintillating LuAG:Pr nanoparticles as an X-ray-to-UV converter for porphyrin-based photodynamic therapy will be discussed.

Seminar 2: Vascular Tree Detection Using Phase Contrast X-Ray Based Imaging (M. Tatíček)

A way of detecting HCC using phase contrast enhanced x-ray imaging combined with computer vision approach in its early stages is presented.

Seminar 3: Soft X-Ray Source Optimization, Diagnostic and Applications (Š. Vondrová)

Emission of Laser Plasma created by 7ns/ 800 mJ Nd:YAG laser beam focused to gas-puff target is investigated.


Part I:

Tuesday 14.1. (room 309)

9:00 – 10:30

Lecture 1, part 1

Ch. Rose-Petruck

10:30 – 11:00

Break

11:00 – 12:30

Lecture 1, part 2

Ch. Rose-Petruck

12:30 – 14:00

Lunch

14:00 – 14:30

Seminar 1

J. Hubner

14:30 – 15:00

Seminar 2

M. Nevrkla

15:00 – 15:30

Seminar 3

M. Tamáš

Wednesday 15.1. (room 309)

9:00 – 10:30

Lecture 2, part 1

Ch. Rose-Petruck

10:30 – 11:00

Break

11:00 – 12:30

Lecture 2, part 2

Ch. Rose-Petruck

 

Part II:

Monday 20.1. (room 309)

9:00 – 10:30

Lecture 1, part 1

N. Lange

10:30 – 11:00

Break

11:00 – 12:30

Lecture 1, part 2

N. Lange

Tuesday 21.1. (room 309)

9:00 – 10:30

Lecture 2, part 1

N. Lange

10:30 – 11:00

Break

11:00 – 12:30

Lecture 2, part 2

N. Lange

12:30 – 14:00

Lunch

14:00 – 14:30

Seminar 1

P. Brůža

14:30 – 15:00

Seminar 2

M. Tatíček

15:00 – 15:30

Seminar 3

Š. Vondrová

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